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Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on their medications.</p> <p>Researchers found out that participants taking this drug for any year, dropped a few pounds within 4 weeks and have kept the load off through the 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which are made up of many active ingredient, which might make them more efficient and safer. </p> <p> Combo-pilling could be the newest fad or even better the newest ahead under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that by right now there are not any long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. 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Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.</p> <p>From a psychiatric point of view, evidence suggests that the ordinary neural mechanism for goal-directed behavior may be hijacked through the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. 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